World Journal of Nephrology and Urology, ISSN 1927-1239 print, 1927-1247 online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Nephrol Urol and Elmer Press Inc
Journal website http://www.wjnu.org

Review

Volume 1, Number 1, February 2012, pages 1-7


Use of Bisphosphonates in Chronic Kidney Disease

Tables

Table 1. Stages of Chronic Kidney Disease
 
StageDescriptionGFR* mL/min/1.73m2
*GFR, glomerular filtration rate.
1Slight kidney damage with normal or increased filtrationMore than 90
2Mild decrease in kidney function60 - 89
3Moderate decrease in kidney function30 - 59
4Severe decrease in kidney function15 - 29
5Kidney failureLess than 15 (or dialysis)

 

Table 2. Bisphosphonate Prescribing Advice for Persons With Reduced Renal Function
 
BisphosphonateRecommendation
GFR: glomerular filtration rate; CrCl: creatinine clearance; min: minute.
AlendronatGFR < 35 ml/min
PamidronatCrCl < 30 ml/min
RisedronatCrCl < 30 ml/min
Ibandronik asidCrCl < 30 ml/min
Zoledronik asidCrCl < 40 ml/min
EtidronatMild and moderate renal disease