World Journal of Nephrology and Urology, ISSN 1927-1239 print, 1927-1247 online, Open Access |
Article copyright, the authors; Journal compilation copyright, World J Nephrol Urol and Elmer Press Inc |
Journal website http://www.wjnu.org |
Review
Volume 1, Number 1, February 2012, pages 1-7
Use of Bisphosphonates in Chronic Kidney Disease
Tables
Stage | Description | GFR* mL/min/1.73m2 |
---|---|---|
*GFR, glomerular filtration rate. | ||
1 | Slight kidney damage with normal or increased filtration | More than 90 |
2 | Mild decrease in kidney function | 60 - 89 |
3 | Moderate decrease in kidney function | 30 - 59 |
4 | Severe decrease in kidney function | 15 - 29 |
5 | Kidney failure | Less than 15 (or dialysis) |
Bisphosphonate | Recommendation |
---|---|
GFR: glomerular filtration rate; CrCl: creatinine clearance; min: minute. | |
Alendronat | GFR < 35 ml/min |
Pamidronat | CrCl < 30 ml/min |
Risedronat | CrCl < 30 ml/min |
Ibandronik asid | CrCl < 30 ml/min |
Zoledronik asid | CrCl < 40 ml/min |
Etidronat | Mild and moderate renal disease |