Salmonella typhi Bacteriuria, Predispositions and Complications: Two Case Reports and Review of Literature

Reetika Dawar, Sanjiv Jasuja, Firdaus Imdadi, Nitin P. Ghonge



Salmonella typhi infection presents most commonly as typhoid fever and infrequently as extraintestinal localized infections of bone, joints, soft tissues, spleen, endocarditis, pulmonary, hepatobiliary, genital and urinary systems. Urinary tract infection (UTI) is rare and clinical presentation is indistinguishable from UTIs due to other etiological agents or may even be asymptomatic. We report two cases of patients with chronic kidney disease with UTI due to Salmonella typhi. Renal cyst, nephrolithiasis and urethral strictures were the concomitant findings in one case and renal tubular acidosis with nephrocalcinosis in the other. In patients with relapses and a chronic course with coexisting functional or structural abnormalities of the urinary tract system, the suspicion of salmonella as one of the probable causative agents should be kept in mind so as to ensure appropriate and adequate therapy. Also in the presence of long-standing hypokalemia, one must investigate for renal abnormalities and vice versa.

World J Nephrol Urol. 2017;6(3-4):32-34


Chronic kidney disease; Nephrocalcinosis; Nephrolithiasis; Salmonella; Urinary tract infection

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World Journal of Nephrology & Urology, quarterly, ISSN 1927-1239 (print), 1927-1247 (online), published by Elmer Press Inc.                     
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