Do Levels of SARS-CoV-2 Anti-Spike Antibody Titers After Vaccination Predict Future Infections in Hemodialysis Patients?

Ramin Sam, Emilio Fernandez

Abstract


Background: There are few data on whether higher severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody titers correlate with subsequent infection in the general population, much less in the dialysis patients.

Methods: Fifty-four hemodialysis patients who had antibody titer measured against SARS-CoV-2 after vaccination were retrospectively looked at after 6 months. Rates of subsequent coronavirus disease 2019 (COVID-19) infection were correlated with initial antibody titers.

Results: The mean antibody titer in the patients who subsequently developed SARS-CoV-2 infection was 437 relative fluorescent units (RFU) as compared with mean antibody titer of 1,436 RFU in patients who did not developed infection.

Conclusion: It seems higher antibody titers are in general protective against subsequent infection; however, some patients developed subsequent infection despite having high antibody titers.




World J Nephrol Urol. 2023;12(1):8-10
doi: https://doi.org/10.14740/wjnu439

Keywords


SARS-CoV-2; COVID-19; Antibody titer; Vaccination

Full Text: HTML PDF
 

Browse  Journals  

     

Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics

World Journal of Oncology

Gastroenterology Research

Journal of Hematology

Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity

Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research

Journal of Neurology Research

International Journal of Clinical Pediatrics

 

 

 

 

 

World Journal of Nephrology & Urology, quarterly, ISSN 1927-1239 (print), 1927-1247 (online), published by Elmer Press Inc.                     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)


This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.wjnu.org   editorial contact: editor@wjnu.org    elmer.editorial@hotmail.com
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada
© Elmer Press Inc. All Rights Reserved.


Disclaimer: The views and opinions expressed in the published articles are those of the authors and do not necessarily reflect the views or opinions of the editors and Elmer Press Inc. This website is provided for medical research and informational purposes only and does not constitute any medical advice or professional services. The information provided in this journal should not be used for diagnosis and treatment, those seeking medical advice should always consult with a licensed physician.